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Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

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Oral azole medicines can be dangerous when taken with nitrates.rollment is required to obtain azole medicines.

Azole medicines can cause a dangerous drop in blood pressure. WARNING: azole medicines can also lower blood pressure if taken with nitrates.

Do not take azole medicines if you are currently using any other medications for HIV or other infections.lanavirine can increase the chance of side effects including dizziness, drowsiness, and headache.

Before taking Cialis, tell your doctor about all of your medical conditions. Especially tell your doctor if you are currently pregnant, planning to conceive, or if you are planning to become pregnant.

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Avoid alcoholic drinks

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Alcohol can increase the chance of side effects including dizziness, drowsiness, and headache.

Alcohol can also cause a dangerous drop in blood pressure. WARNING: alcohol can cause a dangerous drop in blood pressure if taken with Cialis.

Before using Cialis, inform your doctor of all your medical conditions. Some medical conditions may make it necessary for you to use Cialis.

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Ask your doctor about ways to pay for Cialis. eDrugstore can help you save on medications with free delivery charges, including prescription costs. If you are eligible for Cialis, ask your doctor about options such as generic medicines, international mail order options, or alternative medications.

In addition, if you have insurance, call your insurance company directly for extra cost. if you are using eDrugstore, call your insurance company directly for extra cost.

Cialis can cause a dangerous drop in blood pressure.

Before using Cialis, tell your doctor if you are currently using any medication for HIV or other infections. Especially, cialis is a combination of two medicines, azole medicines that work together to increase sexual activity, and eDrugstore.

Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

Cialis FAQsShareileXML

The Caution Needed is cautioned against where Cialis can cause unusual side effects. Report adverse reactions to this drug immediately if you have heart problems, sudden vision problems, low blood pressure, stroke, liver or kidney disease, or a history of serious allergic reactions to medications.

As with all prescription medications, inform your doctor of any and all medications, supplements, and vitamins you are taking. Cialis can interact with these foods and other substances, causing potentially serious adverse reactions.

If you experience changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
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  1. Consider using phosphodiesterase type-5 inhibitors (PDE5 inhibitors) instead of nitrates for Hypertension, as PDE5 inhibitors can reduce blood pressure without directly impacting effectiveness.

Reviewed by: Rick S.

Originally Reviewed: March 20th, 2008

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Table of Contents

  1. 1. What is PDE5 Inhibitors?
  2. 2. PDE5 Inhibitors: Mechanism Of Action Of PDE5 Inhibition
  3. 3. Uses Of PDE5 Inhibitors
  4. 4. Dosage Of PDE5 Inhibitors For Erectile Dysfunction
  5. 5.